A method for treating IgA nephropathy (IgAN) in a subject having IgAN by reducing the expression of CFHR1 or CFHR3, or both, comprising administering therapeutically effective amounts of inhibitory oligonucleotides that reduce the expression of CFHR1 or CFHR3, or both to the subject, wherein the inhibitory oligonucleotides comprise sufficient complementarity to the CFHR1 RNA or CFHR3 RNA to bind thereto under physiological condition.
Covered by US9598733B2
Data downloads available upon purchase.
Disease:
Ig Nepropathy
Accession Type:
HGNC Gene Symbol
Accession Number:
CFHR1 and CFHR3
ACMG:
Compliant
Not compliant
Curated Literature:
Yes
No
Population Data:
Yes
No
Experimental Data:
Yes
No
Case/Segregation:
Yes
No
Evidence Summary:
Yes
No
List of Resources:
Yes
No
Data Download:
Yes